Review



rh mdc ccl22  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    R&D Systems rh mdc ccl22
    Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and <t>rh-MDC/CCL22.</t> The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+
    Rh Mdc Ccl22, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rh+mdc+ccl22/10__1158_slash_0008___5472__can___06___0261-53-6-8?v=R%26D+Systems
    Average 90 stars, based on 7 article reviews
    rh mdc ccl22 - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Specific Recruitment of CC Chemokine Receptor 4–Positive Regulatory T Cells in Hodgkin Lymphoma Fosters Immune Privilege"

    Article Title: Specific Recruitment of CC Chemokine Receptor 4–Positive Regulatory T Cells in Hodgkin Lymphoma Fosters Immune Privilege

    Journal: Cancer Research

    doi: 10.1158/0008-5472.can-06-0261

    Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and rh-MDC/CCL22. The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+
    Figure Legend Snippet: Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and rh-MDC/CCL22. The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+

    Techniques Used: Activity Assay, Control

    Figure 5. The attribution of the chemotactic activity of the supernatant of the HL cell line to TARC/CCL17 and MDC/CCL22 and KM2760-induced inhibition of the migration of CD4+CD25+ T cells. A to C, percentages were determined of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells, obtained from 15 healthy adult volunteers, incubated with KM2760 or Rituximab or without any antibody. Each closed circle represents the percentage of CD4+ cells in each PBMC, CD4+CCR4+ cells in each PBMC, and CD4+CCR4+ cells in each CD4+ cell population. Points, mean; bars, SD. *, P < 0.05, significant differences between each group (n.s., not significant). A 12-hour treatment with KM2760 significantly decreased the proportions of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells. D, the source of the chemotactic activity in the supernatants of the HL cell lines was examined by a chemotaxis assay of human PBL using the neutralizing antibodies antihuman TARC/CCL17 and antihuman MDC/CCL22 mAbs. Antihuman TARC/CCL17 alone or antihuman MDC/CCL22 mAb alone did not completely inhibit the migration of the CD4+CD25+ T cells induced by the supernatant of one of the HL cell lines, HDLM-2, which produces both TARC/CCL17 and MDC/CCL22. In contrast, the presence of both antibodies together caused an almost complete inhibition of the CD4+CD25+
    Figure Legend Snippet: Figure 5. The attribution of the chemotactic activity of the supernatant of the HL cell line to TARC/CCL17 and MDC/CCL22 and KM2760-induced inhibition of the migration of CD4+CD25+ T cells. A to C, percentages were determined of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells, obtained from 15 healthy adult volunteers, incubated with KM2760 or Rituximab or without any antibody. Each closed circle represents the percentage of CD4+ cells in each PBMC, CD4+CCR4+ cells in each PBMC, and CD4+CCR4+ cells in each CD4+ cell population. Points, mean; bars, SD. *, P < 0.05, significant differences between each group (n.s., not significant). A 12-hour treatment with KM2760 significantly decreased the proportions of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells. D, the source of the chemotactic activity in the supernatants of the HL cell lines was examined by a chemotaxis assay of human PBL using the neutralizing antibodies antihuman TARC/CCL17 and antihuman MDC/CCL22 mAbs. Antihuman TARC/CCL17 alone or antihuman MDC/CCL22 mAb alone did not completely inhibit the migration of the CD4+CD25+ T cells induced by the supernatant of one of the HL cell lines, HDLM-2, which produces both TARC/CCL17 and MDC/CCL22. In contrast, the presence of both antibodies together caused an almost complete inhibition of the CD4+CD25+

    Techniques Used: Activity Assay, Inhibition, Migration, Incubation, Chemotaxis Assay



    Similar Products

    rh mdc ccl22  (R&D Systems)
    90
    R&D Systems rh mdc ccl22
    Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and <t>rh-MDC/CCL22.</t> The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+
    Rh Mdc Ccl22, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rh+mdc+ccl22/10__1158_slash_0008___5472__can___06___0261-53-6-8?v=R%26D+Systems
    Average 90 stars, based on 1 article reviews
    rh mdc ccl22 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    recombinant human rh tumor necrosis factor tnf  (R&D Systems)
    90
    R&D Systems recombinant human rh tumor necrosis factor tnf
    Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and <t>rh-MDC/CCL22.</t> The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+
    Recombinant Human Rh Tumor Necrosis Factor Tnf, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rh+mdc+ccl22/10__1152_slash_ajpgi__2001__280__6__g1217-49-0-15?v=R%26D+Systems
    Average 90 stars, based on 1 article reviews
    recombinant human rh tumor necrosis factor tnf - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and rh-MDC/CCL22. The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+

    Journal: Cancer Research

    Article Title: Specific Recruitment of CC Chemokine Receptor 4–Positive Regulatory T Cells in Hodgkin Lymphoma Fosters Immune Privilege

    doi: 10.1158/0008-5472.can-06-0261

    Figure Lengend Snippet: Figure 1. Chemotactic activity of the supernatants of HL cell lines. The chemotactic responses of human PBL induced by the supernatants of HL and ALCL cell lines, rh-TARC/CCL17 and rh-MDC/CCL22. The number of cells migrated (count/AL) into the lower well containing control medium is set as ‘‘one’’ and the relative numbers of cells of each subset migrated into the lower well containing the chemoattractants are presented. Horizontal dotted line, base unit. The supernatants of the HL cell lines did not show any chemotactic activity for whole lymphocytes (A) and CD8+

    Article Snippet: Recombinant human (rh)-TARC/CCL17 (R&D Systems) and/or rh-MDC/ CCL22 (R&D Systems) were used as control chemoattractants.

    Techniques: Activity Assay, Control

    Figure 5. The attribution of the chemotactic activity of the supernatant of the HL cell line to TARC/CCL17 and MDC/CCL22 and KM2760-induced inhibition of the migration of CD4+CD25+ T cells. A to C, percentages were determined of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells, obtained from 15 healthy adult volunteers, incubated with KM2760 or Rituximab or without any antibody. Each closed circle represents the percentage of CD4+ cells in each PBMC, CD4+CCR4+ cells in each PBMC, and CD4+CCR4+ cells in each CD4+ cell population. Points, mean; bars, SD. *, P < 0.05, significant differences between each group (n.s., not significant). A 12-hour treatment with KM2760 significantly decreased the proportions of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells. D, the source of the chemotactic activity in the supernatants of the HL cell lines was examined by a chemotaxis assay of human PBL using the neutralizing antibodies antihuman TARC/CCL17 and antihuman MDC/CCL22 mAbs. Antihuman TARC/CCL17 alone or antihuman MDC/CCL22 mAb alone did not completely inhibit the migration of the CD4+CD25+ T cells induced by the supernatant of one of the HL cell lines, HDLM-2, which produces both TARC/CCL17 and MDC/CCL22. In contrast, the presence of both antibodies together caused an almost complete inhibition of the CD4+CD25+

    Journal: Cancer Research

    Article Title: Specific Recruitment of CC Chemokine Receptor 4–Positive Regulatory T Cells in Hodgkin Lymphoma Fosters Immune Privilege

    doi: 10.1158/0008-5472.can-06-0261

    Figure Lengend Snippet: Figure 5. The attribution of the chemotactic activity of the supernatant of the HL cell line to TARC/CCL17 and MDC/CCL22 and KM2760-induced inhibition of the migration of CD4+CD25+ T cells. A to C, percentages were determined of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells, obtained from 15 healthy adult volunteers, incubated with KM2760 or Rituximab or without any antibody. Each closed circle represents the percentage of CD4+ cells in each PBMC, CD4+CCR4+ cells in each PBMC, and CD4+CCR4+ cells in each CD4+ cell population. Points, mean; bars, SD. *, P < 0.05, significant differences between each group (n.s., not significant). A 12-hour treatment with KM2760 significantly decreased the proportions of CD4+ cells in PBMC, CD4+CCR4+ cells in PBMC, and CD4+CCR4+ cells in CD4+ cells. D, the source of the chemotactic activity in the supernatants of the HL cell lines was examined by a chemotaxis assay of human PBL using the neutralizing antibodies antihuman TARC/CCL17 and antihuman MDC/CCL22 mAbs. Antihuman TARC/CCL17 alone or antihuman MDC/CCL22 mAb alone did not completely inhibit the migration of the CD4+CD25+ T cells induced by the supernatant of one of the HL cell lines, HDLM-2, which produces both TARC/CCL17 and MDC/CCL22. In contrast, the presence of both antibodies together caused an almost complete inhibition of the CD4+CD25+

    Article Snippet: Recombinant human (rh)-TARC/CCL17 (R&D Systems) and/or rh-MDC/ CCL22 (R&D Systems) were used as control chemoattractants.

    Techniques: Activity Assay, Inhibition, Migration, Incubation, Chemotaxis Assay